Tumor treatment process and composition

US4895874A · kind A · utility

Assignees

• David Rubin · IL
• Ely J. Rubin · US
• Adolf W. Schwimmer · US
• Irwin S. Schwartz · IL
• CENTER LABORATORIES, INC. · TW

Inventors

• David Rubin · San Diego, US
• Ely Rubin · Jerusalem, IL

Key dates

• Filing date: Mar 1, 1984
• Grant date: Jan 23, 1990
• Expiry date: Mar 1, 2004

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/20
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Saturated aliphatic straight chain dicarboxylic acids having a total number of carbon atoms which are divisible by four, are selectively toxic to certain tumor cells while non-toxic to normal cells of the same origin. Octacosanedioic acid is particularly preferred as it is a component of normal blood serum. Compositions containing these compounds may be used in the treatment of certain malignancies.