Non-radioactive carbodiimide precursor to nucleic acid probes
US4895955A · kind A · utility
18Cited by
1References
4Claims
0Family size
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Key dates
| Filing date | May 27, 1988 |
| Grant date | Jan 23, 1990 |
| Priority date | — |
| Expiry date | May 27, 2008 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to carbodiimide compounds of the formula: EQU Z--L--W--N.dbd.C.dbd.N--R.sub.1 wherein Z is a signalling moiety or a protecting group; L is a divalent linking group; W is an alkylene group having up to 24 carbon atoms which can be substituted or interrupted by a water solubility enhancing group or cleavable S--S group; and R.sub.1 is an alkyl group having up to 18 carbon atoms. These compounds are useful in the nonradioactive labelling of nucleic acid probes, and methods employing same.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.