Imidazolines useful in lowering intraocular pressure
US4897412A · kind A · utility
3Cited by
7References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 19, 1989 |
| Grant date | Jan 30, 1990 |
| Priority date | — |
| Expiry date | Jan 19, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D233/50
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Antiglaucoma compounds having beta adrenoreceptor antagonist properties and alpha adrenoreceptor antagonist properties are described. The compounds comprise a beta blocker-derived moiety designed to provide beta antagonist properties and an imidazolidine moiety designed to provide alpha-antagonist properties. Methods of synthesizing the compounds are also described. The compounds are useful in the treatment of glaucoma due to their ability to lower elevated intraocular pressure.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.