Prodrugs of 3,4-hydroxy benzoyloxypropanolamines
US4897417A · kind A · utility
5Cited by
6References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 15, 1988 |
| Grant date | Jan 30, 1990 |
| Priority date | — |
| Expiry date | Dec 15, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/24
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
In accordance with the present invention, disclosed herein are compounds of the formula ##STR1## wherein R is straight or branched loweralkyl, R.sub.1 is hydrogen, straight or branched loweralkyl, lowercycloalkyl, amino, loweralkoxy or acylamino, and R.sub.2 is straight or branched loweralkyl, amino, cyclohexyl, morpholino, piperidino, tetrahydrofuranyl, dihydrofuranyl, tetrahydropyranyl, dioxolanyl, 2,2-dimethyl dioxolanyl, dioxanyl, pyrrolidinyl, tetrahydrooxazolyl, and dihydrooxazolyl, and pharmaceutically acceptable salts thereof. The compounds are useful in the treatment of glaucoma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.