Intermediates for the preparation of antihypercholesterolemic tetrazole compounds
US4898949A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 18, 1988 |
| Grant date | Feb 6, 1990 |
| Priority date | — |
| Expiry date | Feb 18, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/6524
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention provides novel tetrazole intermediates of the formula ##STR1## wherein R.sup.1 and R.sup.4 each are independently hydrogen, halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy or trifluoromethyl; PA0 R.sup.2,R.sup.3,R.sup.5 and R.sup.6 each are independently hydrogen, halogen, C.sub.1-4 alkyl or C.sub.1-4 alkoxy; PA0 B is hydrogen, C.sub.1-4 alkoxycarbonyl, CH.sub.2 Y or CH.sub.2 Z; PA0 Y is hydrogen, hydroxyl or X; PA0 Z is ##STR2## X is bromo, chloro or iodo; R.sup.10 is C.sub.1-4 alkyl; and PA0 R.sup.11 is phenyl which is unsubstituted or substituted by one or two C.sub.1-4 alkyl or chloro substituents. and processes thereof which are useful for the preparation of antihypercholesterolemic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.