Method of reducing glial scar formation and promoting axon and blood vessel growth and/or regeneration through the use of activated immature astrocytes
US4900553A · kind A · utility
40Cited by
8References
57Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 11, 1987 |
| Grant date | Feb 13, 1990 |
| Priority date | — |
| Expiry date | Sep 11, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to "activated" immature astrocytes and methods of utilizing the activated immature astrocytes to reduce secondary necrosis and scar formation in central nervous system tissue as well as to promote axon and/or blood vessel growth or regeneration. In specific embodiments of the invention, activated immature astrocytes are used in injectable form or on a polymer implant. The activated immature astrocytes and pharmaceutical compositions comprising same, may be used to treat disorders of the nervous system resulting from accidents or diseases which have in some way damaged the nerve tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.