Methods and compositions for prophylactic and therapeutic treatment of infections
US4900722A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 1, 1988 |
| Grant date | Feb 13, 1990 |
| Priority date | — |
| Expiry date | Aug 1, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08B37/0024
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
A new class of soluble phosphorylated glucans is described as well as the process for making the same. According to one embodiment, the soluble phosphorylated glucan is derived from the yeast Saccharomyces cerevisiae. The soluble phosphorylated glucans are useful for prophylactic and therapeutic applications against neoplastic, bacteria, viral, fungal and parasitic diseases. The soluble phosphorylated glucans are used either alone or in combination with a known antimicrobial agent for prophylactic and therapeutic antimicrobial applications. Additionally, they may be administered as a non-toxic adjuvant, in combination with chemotherapy. The soluble phosphorylated glucans are also useful for stimulating macrophage cells, either in vivo or in vitro, to produce a cytotoxic/cyctostatic factor effective against cancer cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.