Steroids including a spiro ring in position 17, the process for their preparation and their use

US4900725A · kind A · utility

Assignee

• Roussel Uclaf · FR

Inventors

• Francois Nioue · Les Pavillons-sous-Bois, FR
• Lucien Nedelec · Le Raincy, FR
• Daniel Philibert · Thourotte, FR
• Martine Moguilewsky · Paris, FR

Key dates

• Filing date: Nov 25, 1987
• Grant date: Feb 13, 1990
• Expiry date: Nov 25, 2007

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07J41/0083
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

##STR1## Products having the formula (I) wherein R.sub.1 is an aryl or aralkyl, R.sub.2 is a hydrocarbonated radical (1-18 carbon atoms), the dotted lines indicate an optional bond, the cycles A, B and C represent (II), (III), (IV), (V), (VI); R' and R" are H, alkyl (1-4 carbon atoms). Re is H, alkyl (1-6 carbon atoms), acyl, and their salts, their preparation, their application as medicaments, the pharmaceutical compositions containing them and intermediaries.