Method of inactivating reproducible filterable pathogens in blood plasma products

US4904641A · kind A · utility

Assignee

• Immuno Aktiengesellschaft fur chemisch-medizinische Produkte · AT

Inventors

• Johann Eibl · Wien, AT
• Otto Schwarz · Waldshut-Tiengen, DE
• Fritz Elsinger · Wien, AT
• Gunter Wober · Oberwaltersdorf, AT
• Anton Philapitsch · Staprijk, AT
• Yendra Linnau · Wien, AT
• Friedrich Dorner · Wien, AT
• Karl Trambauer · Wien, AT
• Wolfgang Frechinger · Wien, AT

Key dates

• Filing date: Jan 3, 1989
• Grant date: Feb 27, 1990
• Expiry date: Jan 3, 2009

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2/0023
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

There is disclosed a method of inactivating reproducible filterable pathogens in blood plasma products by applying elevated temperatures. The blood plasma products are heat treated in a solid state in a closed inactivation container in the presence of specific amounts of water and organic compounds, provided that the water substantially remains physically bound to the blood plasma products, while the organic compound is present in a gaseous form in the atmosphere. The water content of the blood plasma products is 0.08 to 0.40. The concentration of the organic compounds in the gaseous phase is 0.01 to 10 g per liter of container volume.