Patent · US Expired

Process for the preparation of unsymmetrical dihydropyridines

US4904789A · kind A · utility

0Cited by

0References

4Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Paul Naab · Bad Reichenhall, DE
Willi Lange · Wuppertal, DE
Werner Teller · Wuppertal, DE

Key dates

Filing date	Nov 23, 1988
Grant date	Feb 27, 1990
Priority date	—
Expiry date	Nov 23, 2008

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D211/90
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

In the preparation of nitrenedipine by reaction of an ylidene compound of the formula ##STR1## with an enamine compound of the formula ##STR2## the improvement which comprises effecting the reaction in the presence of a catalytic amount of diisopropylamine acetate or dimethylbenzylamine acetate. The product is produced in high yield with reduced amounts of symmetrical by-products.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.