Appropriate cytotoxic pharmaceutical combination especially for the treatment of cancers
US4906469A · kind A · utility
5Cited by
2References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 15, 1988 |
| Grant date | Mar 6, 1990 |
| Priority date | — |
| Expiry date | Jan 15, 2008 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/828
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a cytotoxic pharmaceutical combination comprising: PA0 at least a first antibody possessing the capacity of selective recognition of a target antigen or antigens carried by cells to be destroyed, the said antibody being characteristic of an animal species different from that of the target cells, PA0 at least one cytotoxic conjugate obtained by covalent bond coupling of the A chain of ricin with a second antibody specific for immunoglobins of the animal species to which the said first antibody or antibodies belong.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.