Biodegradable poly(hydroxyalkyl)amino dicarboxylic acid) derivatives, a process for their preparation, and the use thereof for depot formulations with controlled delivery of active ingredient

US4906473A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Hubert Bader · Mainz, DE
• Diether Ruppel · Frankfurt am Main, DE
• Axel Walch · Baldham, DE

Key dates

• Filing date: Dec 31, 1987
• Grant date: Mar 6, 1990
• Expiry date: Dec 31, 2007

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/5031
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to biodegradable poly((hydroxyalkyl)amino dicarboxylic acid) derivatives of the formula I ##STR1## in which n, m, x, y, z, R and R' have the indicated meanings, and to a process for their preparation and to the use thereof for depot formulations with controlled delivery of active ingredient.