Method for the preparation of 4'-(substituted)-amino-2-(substituted) amino-3',5'-dichloroacetophenone and salts thereof
US4906781A · kind A · utility
1Cited by
2References
5Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jan 24, 1989 |
| Grant date | Mar 6, 1990 |
| Priority date | — |
| Expiry date | Jan 24, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C225/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for the preparation of 4'-(substituted)-amino-2-(substituted)amino-3',5'-dichloroacetophenone and salts thereof. The method involves the chlorination of the corresponding 4'-(substituted)amino-2-(substituted) aminoacetophenone and acid addition salts thereof in the presence of an anhydrous or aqueous solvent selected from ethyl alcohol, t-butyl alcohol and acetic acid. The invention describes the preparation of 4'-amino-2-(t-butylamino)-3',5'-dichloroacetophenone and the hydrochloride thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.