Process for producing amides by use of microoganisms
US4908313A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 10, 1987 |
| Grant date | Mar 13, 1990 |
| Priority date | — |
| Expiry date | Dec 10, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P13/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
In a process for hydrating a nitrile compound by the action of a microorganism having nitrilase activity to convert the nitrile compound into the corresponding amide compound, the performances such as yield and reaction velocity are markedly enhanced by irradiation of the microorganism with light. The process of the present invention is characterized in that (a) the microorganism having nitrilase activity is a positive gram-staining microorganism, (b) the microbial cells are allowed to accept light energy of at least about 1.times.10.sup.-2 .mu.E/g microbial cells second before termination of the hydration reaction, and (c) the hydration reaction is carried out in a vessel composed at least partly of a non-light transmitting material.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.