Hyperosmotic/hyperoncotic solutions for resuscitation of hypodynamic shock
US4908350A · kind A · utility
56Cited by
5References
20Claims
0Family size
Assignee
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Key dates
| Filing date | Feb 24, 1988 |
| Grant date | Mar 13, 1990 |
| Priority date | — |
| Expiry date | Feb 24, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K33/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A physiologically acceptable solution which is both hyperosmotic and hyperoncotic with respect to blood plasma and has utility in treating patients experiencing or threatening to experience hypodynamic shock. The physiologically acceptable solution comprises a hyperosmotic concentration of a crystalloid (in excess of about 1800 mOsms) and hyperoncotic concentration of a colloid (in excess of about 30 mm Hg). The physiologically acceptable solution is easily administered by single, rapid infusion of approximately 4 to 5 ml/kg of body weight and results in a rapid and sustained normalization of circulatory function.
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