Targeted enternal delivery system
US4910021A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 25, 1986 |
| Grant date | Mar 20, 1990 |
| Priority date | — |
| Expiry date | Nov 25, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A capsule for oral administration of a pharmaceutically active ingredient contains a pharmaceutical composition comprising the active ingredient, for example, a peptide, an absorption promoter and usually, a carrier. The absorption promoter is capable of enhancing absorption of the active ingredient from the intestine into the bloodstream. The capsule is coated with a film forming composition, which film is sufficiently insoluble at a pH below 7 as to be capable of protecting the capsule and its contents from the digestive juices until the capsule reaches a region below the upper part of the intestine, whereupon the coating and capsule are capable of eroding or dissolving to release the active ingredient for absorption into the bloodstream.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.