Imidazolylguanidine derivatives and compositions containing these compounds

US4912119A · kind A · utility

Assignee

• Heumann Pharma GmbH · DE

Inventors

• Armin Buschauer · Berlin, DE
• Helmut Schickaneder · Eckental, DE
• Peter Morsdorf · Langenzenn, DE
• Walter Schunack · Berlin, DE
• Gert Baumann · Pittsburgh, US
• Kurt H. Ahrens · Nürnberg, DE

Key dates

• Filing date: Sep 14, 1987
• Grant date: Mar 27, 1990
• Expiry date: Sep 14, 2007

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D409/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

New imidazolyl guanidine derivatives corresponding to the following general formula ##STR1## are described. These compounds may be used in cardiac diseases, certain forms of hypertension and in diseases of arterial occlusion on account of their agonistic action on histamine-H.sub.2 receptors and in part their additional H.sub.1 -antagonistic receptor activity.