Preparation and use of new solvates of beclomethasone 17,21-dipropionate
US4913892A · kind A · utility
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11Claims
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Key dates
| Filing date | Jul 24, 1985 |
| Grant date | Apr 3, 1990 |
| Priority date | — |
| Expiry date | Jul 24, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J5/0076
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Preparation of novel solvates of beclomethasone 17,21-dipropionate, by dissolution of beclomethasone 17,21-dipropionate in an ethereal or halogenated hydrocarbon solvent and precipitation by the addition of di-isopropyl ether. These new solvates are bulk stable, in both the micronized and non-micronized forms. The micronized form is especially suitable for the preparation of stable aerosol.
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