Novel phosphoric diesters
US4914197A · kind A · utility
27Cited by
1References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 4, 1987 |
| Grant date | Apr 3, 1990 |
| Priority date | — |
| Expiry date | Mar 4, 2007 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel phosphoric diesters of general formula: ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and each means a methyl group or a hydrogen atom, provided that at least one of R.sub.1 and R.sub.2 is a hydrogen atom, or a salt thereof which can be produced by reacting .beta., .gamma. or .delta.-tocopherol with a halophosphorylating agent such as phosphorus oxychloride, reacting the resultant product with ascorbic acid whereof hydroxyl groups at 5- and 6-positions are protected, and then removing protected groups from the hydroxyl groups. The phosphoric diester has antiinflammatory activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.