Optically active salts of a substituted thiazolidine-4-carboxylate and 3-chloro-2-hydroxypropyltrimethyl ammonium, their preparation and use

US4914208A · kind A · utility

Assignee

• Degussa AG · DE

Inventors

• Harald Jakob · Hasselroth, DE
• Klaus Huthmacher · Gelnhausen, DE
• Herbert Klenk · Hanau, DE
• Axel Kleemann · Hanau, DE
• Gunes Giray · Kleinostheim, DE

Key dates

• Filing date: Oct 17, 1988
• Grant date: Apr 3, 1990
• Expiry date: Oct 17, 2008

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D277/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to the preparation of optically active salts of the general formula ##STR1## from which the corresponding optically active 3-chloro-2-hydroxypropyltrimethyl ammonium chloride can be obtained by treatment with mineral acid. The L(-) form of this compound is a valuable component for the synthesis of L(-) carnitine.