Antitumor composition comprising pyrimidine type nucleic acid derivative and 1-[(2-hydroxyethoxy)methyl]uracil derivative
US4916121A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 7, 1986 |
| Grant date | Apr 10, 1990 |
| Priority date | — |
| Expiry date | May 7, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/70
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An antitumor agent comprising (i) at least one pyrimidine type nucleic acid derivative having the general formula (I): ##STR1## wherein X represents a fluorine atom or a trifluoromethyl group, R.sup.1 and R.sup.2 may be the same or different and represent a hydrogen atom or an acyl group, R.sup.3 represents a hydrogen atom or a hydroxyl group, and (ii) at least one 1-[(2-hydroxyethoxy)methyl]uracil derivative having the general formula (II): ##STR2## wherein Y represents a hydrogen atom, a halogen atom, a methyl group, a benzyl group, a benzyloxybenzyl group, a vinyl group, a nitro group, or an amino group and R.sup.4 represents a hydrogen atom or an acyl group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.