Cyanoisoalkylation of hydroxy substituted aryl compounds using ketones
US4916251A · kind A · utility
2Cited by
8References
20Claims
0Family size
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Key dates
| Filing date | Jan 2, 1987 |
| Grant date | Apr 10, 1990 |
| Priority date | — |
| Expiry date | Jan 2, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C255/36
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for cyanoisoalkylating phenols or other hydroxy-substituted aryl compounds, which may have up to two substitutents ortho or para to the hydroxy moiety, comprising reacting a molar excess of phenol or aryl compound with a ketone in the presence of cyanide ion and hydroxide ion at an elevated temperature. Compounds, such as 4-(1-cyano-1-methylethyl)phenol, produced via this method are useful as chemical intermediates in the preparation of polyurethanes, epoxy resins and pharmaceutical and agricultural products.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.