Drug delivery article

US4917119A · kind A · utility

Assignee

• R.J. REYNOLDS TOBACCO COMPANY · US

Inventors

• Dennis Lee Potter · Kernersville, US
• Mark L. Raker · Winston-Salem, US
• Henry T. Ridings · Lewisville, US
• Andrew J. Sensabaugh, Jr. · Winston-Salem, US
• Amos E. Westmoreland · Winston-Salem, US
• Donna K. Woods · Winston-Salem, US
• Chandra Kumar Banerjee · Clemmons, US

Key dates

• Filing date: Nov 30, 1988
• Grant date: Apr 17, 1990
• Expiry date: Nov 30, 2008

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A24F42/10
• WIPO field: Other consumer goods
• WIPO sector: Other fields

Abstract

A drug delivery article provides a dose of a volatilized drug by heating a drug carrying substrate, but not burning any material. A heat source which includes a metal oxide (e.g., calcium oxide), an anhydrous metal sulfate (e.g., magnesium sulfate), an inorganic salt and a sugar, generates heat upon contact of water therewith. The heat produced by the heat source heats the drug in a heat exchange relationship therewith. The drug volatilizes and is drawn into the mouth of the user of the article. Typical heat sources heat the drug to a temperature within 70.degree. C. to 200.degree. C. for 4 to 8 minutes.