2-substituted arabinopyranosyl nucleosides and nucleotides
US4918056A · kind A · utility
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7Claims
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Key dates
| Filing date | Oct 14, 1986 |
| Grant date | Apr 17, 1990 |
| Priority date | — |
| Expiry date | Oct 14, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/24
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel arabinopyranosyl nucleoside derivatives having the heterocyclic moiety and fluorine at the 2' position of the sugar ring (pyranose configuration), which have antitumor, antiviral and antimicrobial properties, are prepared by condensation of a pyrimidine, purine or 1,3-oxazine base with an acylated 2-deoxy-2,2-difluoro-D-arabinopyranoside and/or acylated 2-deoxy-2-bromo-2-fluoro-D-arabinopyranoside.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.