Treating alcohol addiction with 1,4-dihydropyridine derivatives

US4918076A · kind A · utility

Assignee

• Troponwerke GmbH & Co. KG · DE

Inventors

• Klaus Opitz · Münster, DE
• Jorg Traber · Lohmar, DE

Key dates

• Filing date: Feb 22, 1989
• Grant date: Apr 17, 1990
• Expiry date: Feb 22, 2009

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/32
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method of treating a patient afflicted with alcohol addiction which comprises administering to such patient an amount effective therefor of a dihydropyridine of the formula ##STR1## in which R.sup.1 is one or two substituents independently selected from the group consisting of nitro, halogen, trifluoromethyl and OCHF.sub.2, PA0 R.sup.2 and R.sup.3 each independently is alkyl with 1 to 12 carbon atoms optionally substituted by alkoxy with 1 to 4 C atoms, hydroxyl, halogen or N-methyl-N-benzylamino, and PA0 R.sup.4 is cyano or alkyl with 1 to 4 carbon atoms optionally substituted by hydroxyl or halogen.