4,5 Dihydroimidazole compounds which have useful pharmaceutical utility
US4918083A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 24, 1987 |
| Grant date | Apr 17, 1990 |
| Priority date | — |
| Expiry date | Nov 24, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound of formula (I): ##STR1## or a pharmaceutically acceptable salt, ester or amide thereof, or a pharmaceutically acceptable solvate thereof, wherein: Z represents a residue of a substituted or unsubstituted aryl group, A.sup.1 represents a substituted or unsubstituted methylene group or a substituted or unsubstituted ethylene group; A.sup.2 represents a substituted or unsubstituted methylene group or a substituted or unsubstituted ethylene group; providing that at least one of A.sup.1 or A.sup.2 represents a substituted methylene group or a substituted ethylene group, X represents O or NR.sup.o wherein R.sup.o represents a hydrogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted aryl group, an alkanoyl group substituted or unsubstituted in the alkyl moiety, or an arylalkyl moiety substituted or unsubstituted in the aryl moiety, p represents an integer 2 or 3, and q represents an integer in the range of from 1 to 12; a process for preparing such a compound, a composition comprising such a compound and the use of such a compound in medicine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.