Conjugates in which a monovalent carboxylic ionophore is associated by means of a covalent bond with a macromolecule, their use as immunotoxin potentiators and the intermediate activated ionophores
US4919928A · kind A · utility
3Cited by
3References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 6, 1987 |
| Grant date | Apr 24, 1990 |
| Priority date | — |
| Expiry date | Apr 6, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/01
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to conjugates in which a monovalent carboxylic ionophore is associated by means of a covalent bond with a macromolecule chosen from antibodies, fragments of antibodies, and peptide ligands. It also relates to the activated ionophores. These conjugates are suitable as immunotoxin potentiators.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.