Method for stabilizing extra-chromosomal elements in bacteria during cultivation
US4920048A · kind A · utility
23Cited by
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10Claims
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Key dates
| Filing date | Dec 10, 1985 |
| Grant date | Apr 24, 1990 |
| Priority date | — |
| Expiry date | Dec 10, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/75
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for stabilization of extra-chromosomal elements in bacteria during cultivation which comprises transformation of a host bacterium having a defect in a chromosomal gene needed for the synthesis or maintenance of the cell envelope with an extra-chromosomal element capable of complementing the chromosomal gene defect of the host bacterium, the extra-chromosomal element also including an expressible DNA-sequence coding for a desired product.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.