Selected removal of trityl groups from trispa
US4920207A · kind A · utility
3Cited by
2References
13Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 17, 1987 |
| Grant date | Apr 24, 1990 |
| Priority date | — |
| Expiry date | Sep 17, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H13/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
2,3,4,3',4'-penta-O-acetyl sucrose (4-PAS), a key intermediate in the preparation of sucralose, is prepared by the selective removal of trityl groups from 6,1', 6'-tri-O-trityl-penta-O-acetyl sucrose (TRISPA) in which a catalytic amount of an aralkyl chloride or hydrogen chloride is added to a solution of TRISPA is an inert organic solvent is hydrogenated in the presence of a hydrogenolysis catalyst such a platinum or palladium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.