Novel hydroxide mediated FK-506 rearrangement process
US4920218A · kind A · utility
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10Claims
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Key dates
| Filing date | Sep 5, 1989 |
| Grant date | Apr 24, 1990 |
| Priority date | — |
| Expiry date | Sep 5, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is described involving an alkaline rearrangement of FK-506 producing a new decarbonylated 22-membered macrocycle rearrangement derivative of FK-506, i.e. C.9, nor-keto FK-506.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.