Mucin directed lipsome
US4921644A · kind A · utility
60Cited by
7References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 29, 1988 |
| Grant date | May 1, 1990 |
| Priority date | — |
| Expiry date | Feb 29, 2008 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2989
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Mucin coated Sepharose is used as a laboratory model to measure the affinity of a postulated lipid composition in liposome configuration for binding to mucin. The preferred lipid composition provides a first lipid moiety which projects a postive charged ion. A second lipid moiety enhances the positive charge by neutralizing all intermediate negative charges of the first lipid. The result is a liposome with strong postive charge areas which will bind to mucin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.