Angiogenic and blood perfusion inducing properties of amphiphilic compounds
US4921838A · kind A · utility
26Cited by
9References
8Claims
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Key dates
| Filing date | Jun 16, 1987 |
| Grant date | May 1, 1990 |
| Priority date | — |
| Expiry date | Jun 16, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/765
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for enhancing angiogenesis and/or blood vascular perfusion in mammals by administering a pharmacologically effective amount of specific angiogenically active non-ionic, anionic, cationic and zwitterionic amphiphilic compounds. An angiogenically effective amount of the angiogenically active compound digitonin is in the range of at least 1.25 microgram to at least 200 microgram of digitonin. The range including enhancement of vascular perfusion is up to 50 mg of digitonin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.