Platinum complexes with one radiosensitizing ligand
US4921963A · kind A · utility
37Cited by
4References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 13, 1987 |
| Grant date | May 1, 1990 |
| Priority date | — |
| Expiry date | Apr 13, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Complexes of platinum II containing a single radiosensitizer ligand and an amino or ammine substituent shows superior binding to DNA and are useful in chemotherapy and sensitization of hypoxic tumors to radiation. The chemotherapeutic value of these compounds is enhanced by administration of vasoactive agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.