Quinazoline substituted aminomethyl benzene derivatives
US4923873A · kind A · utility
0Cited by
3References
16Claims
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Assignee
Inventors
Key dates
| Filing date | May 18, 1987 |
| Grant date | May 8, 1990 |
| Priority date | — |
| Expiry date | May 18, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/38
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to new compounds of the formula ##STR1## where X is ##STR2## alkylene, or --S-- where R.sub.1 is hydrogen, alkyl, or aryl; W is hydrogen, hydroxy, amino, alkyloxy, aryloxy, O-alkyl, or O-aralkyl; (Y).sub.A) is --CH.sub.2 NR.sub.2 R.sub.3 where R.sub.2 and R.sub.3 may be hydrogen, substituted alkyls, aryls, or together with N form a 5 to 7 membered heterocyclic group; and Ar is a substituted or unsubstituted aryl. These compounds are useful in the treatment of various cardiac arrhythmias.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.