Patent · US Expired

2,',5'-phosphorothioate oligoadenylates and plant antiviral uses thereof

US4924624A · kind A · utility

38Cited by

0References

35Claims

0Family size

Assignee

Temple University-Of The Commonwealth System of Higher Education · US

Inventors

Robert J. Suhadolnik · Roslyn, US
Wolfgang Pfleiderer · Konstanz, DE

Key dates

Filing date	Oct 22, 1987
Grant date	May 15, 1990
Priority date	—
Expiry date	Oct 22, 2007

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P31/12
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Optically active compounds of the formula ##STR1## wherein n is 1 or 2 and m is 0, 1, 2 or 3 have antiviral activity. Compounds of the formula wherein at least one of the internucleotide phosphorothioate linkages is of the Sp configuration possess increased antiviral activity and/or metabolic stability.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.