Aromatic esters and thioesters and their use in human or veterinary medicine and in cosmetic compositions
US4925658A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 19, 1989 |
| Grant date | May 15, 1990 |
| Priority date | — |
| Expiry date | Jan 19, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/74
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Aromatic esters and thioesters have the formula ##STR1## wherein X represents oxygen or sulfur, PA1 R.sub.1 represents --CH.sub.2 OH, --CH(OH)--CH.sub.3, --COOR.sub.5 or ##STR2## R.sub.5 represents hydrogen, lower alkyl, lower alkenyl, monohydroxyalkyl or polyhydroxyalkyl, PA1 r' and r" represent hydrogen, lower alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl or benzyl optionally substituted, the residue of an amino acid or aminated sugar, or taken together form a heterocycle, PA1 R.sub.2 represents .alpha.,.alpha.'-disubstituted alkyl having 4-12 carbon atoms or mono- or polycyclic cycloalkyl having 5-12 carbon atoms whose carbon linking carbon is trisubstituted, PA1 R.sub.3 represents hydrogen, lower alkyl, or --Si(CH.sub.3).sub.2 R'.sub.3 wherein R'.sub.3 represents lower alkyl, and PA1 R.sub.4 represents hydrogen or lower alkyl, and PA1 the salts of these aromatic esters and thioesters of formula (I) when R.sub.5 represents hydrogen. These aromatic esters and thioesters can be used in human and veterinary medicine and in cosmetic formulations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.