Arylcyclobutylmethylamines
US4925879A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 1, 1988 |
| Grant date | May 15, 1990 |
| Priority date | — |
| Expiry date | Aug 1, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D317/28
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula I ##STR1## and pharmaceutically acceptable salts thereof; in which R.sub.1 and R.sub.2, which are the same or different, are H or an optionally substituted hydrocarbon group or R.sub.1 and R.sub.2 together with the nitrogen atom to which they are attached form an optionally substituted heterocyclic ring; PA1 R.sub.3 is an optionally substituted aromatic hydrocarbon group; and PA1 R.sub.4 is a hydrocarbon group containing at least one substituent selected from the group consisting of hydroxy and acylated derivatives thereof, optionally substituted alkoxy groups, optionally substituted cycloalkyloxy groups, optionally substituted alkylenedioxy groups, oxo and groups of formula S(O).sub.p R.sub.5 in which p is 0, 1 or 2 and R.sub.5 is an alkyl group, said hydrocarbon group being optionally substituted by additional substituents, PA1 are useful in the treatment of depression.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.