Process for preparing 1-alkyl-5-nitroimidazoles
US4925949A · kind A · utility
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Key dates
| Filing date | Jan 13, 1989 |
| Grant date | May 15, 1990 |
| Priority date | — |
| Expiry date | Jan 13, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D233/94
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Process for preparing 1-alkyl-5-nitroimidazoles of formula: ##STR1## which comprises reacting an alkyl sulphate with an imidazole derivative of general formula: ##STR2## in an organic solvent, and then hydrolyzing or alcoholyzing the product obtained. In the formulae (I) and (II), R denotes hydrogen, unsubstituted or substituted alkyl, aryl or cycloalkyl. In the formula (I), R.sub.1 denotes alkyl. In the formula (II), X denotes a group which can be removed by hydrolysis or alcoholysis.
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