Patent · US Expired

Process for preparing 1-hydroxyalkyl-5-nitroimidazoles

US4925952A · kind A · utility

12Cited by
2References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 13, 1989
Grant dateMay 15, 1990
Priority date
Expiry dateJan 13, 2009

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D233/94
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Process for preparing 1-(hydroxyalkyl)nitroimidazoles of formula: ##STR1## which comprises reacting an alkylene sulphate of formula: ##STR2## with an imidazole derivative of formula: ##STR3## followed by hydrolyzing or alcoholyzing the product obtained. In the formulae (I) and (II), n is 2 or 3; in the formulae (I) and (III), R denotes hydrogen or hydrocarbon radical; and in the formula (III), X denotes hydrogen or a radical that can be removed by hydrolysis or alcoholysis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.