Resolution of (1S,4R)-1-ethyl-1,3,4,9-tetrahydro-4-(phenylmethyl) pyrano[3,4-B]indole-1-acetic acid using brucine
US4925955A · kind A · utility
1Cited by
4References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 28, 1989 |
| Grant date | May 15, 1990 |
| Priority date | — |
| Expiry date | Feb 28, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to a process for resolving (.+-.)-cis-1-ethyl-1,3,4,9-tetrahydro-4-(phenylmethyl)pyrano[3,4-b]indole- 1-acetic acid (pemedolac) usinig brucine to obtain the corresponding (1S,4R)-eutomer. Said eutomer is useful as an analgesic.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.