Patent · US Expired

Method of producing fibrin-specific monoclonal antibodies lacking fibrinogen-cross-reactivity using fibrin-specific peptides

US4927916A · kind A · utility

38Cited by
4References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 30, 1986
Grant dateMay 22, 1990
Priority date—
Expiry dateJan 30, 2006

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S530/812
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Peptides comprising fibrin-specific epitopic sequences are used to prepare hybridoma cell lines producing antifibrin-specific monoclonal antibodies substantially devoid of fibrinogen-cross-reactivity obtained by somatic cell fusion. The antibodies are useful for the in vivo and in vitro detection of thrombi and fibrin deposits.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.