Method of preparing a cryoprecipitated suspension and use thereof
US4928603A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 6, 1988 |
| Grant date | May 29, 1990 |
| Priority date | — |
| Expiry date | Jun 6, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/418
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
This invention concerns a method of preparing a cryoprecipitated suspension containing fibrinogen and Factor XIII useful as a precursor in the preparation of a fibrin glue which involves (a) freezing fresh frozen plasma from a single donor such as a human or other animal, e.g., a cow, sheep or pig, which has been screened for blood transmitted diseases, e.g., one or more of syphilis, hepatitis or acquired immune deficiency syndrome at about -80.degree. C. for at least 6 hours, preferably for at least about 12 hours; (b) raising the temperature, so as to form a supernatant and a cryoprecipitated suspension containing fibrinogen and Factor XIII; and (c) recovering the cryopricipitated suspension.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.