Patent · US Expired

Process for producing L(-)-tetrahydrofolic acid

US4929551A · kind A · utility

3Cited by
0References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 15, 1989
Grant dateMay 29, 1990
Priority date
Expiry dateAug 15, 2009

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/849
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The invention relates to a process for producing L(-)-tetrahydrofolic acid which comprises allowing dihydrofolate reductase to act upon dihydrofolic acid in the presence of (1) NADP or NADPH, and (2) glucose and glucose dehydrogenase. L(-)-tetrahydrofolic acid is useful as the intermediate for L(-)-leucovarin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.