Patent · US Expired

Optically-active isomers of dideoxycarbocyclic nucleosides

US4931559A · kind A · utility

19Cited by
8References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 5, 1988
Grant dateJun 5, 1990
Priority date
Expiry dateDec 5, 2008

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P35/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Antiviral and antitumor compounds are disclosed of general formula: ##STR1## wherein Z is H, OR' or NH.sub.2, wherein R' is H, (C.sub.1 -C.sub.4)alkyl, aryl, CHO, (C.sub.1 -C.sub.16)alkanoyl or O.dbd.P(OH).sub.2, Y is CH or N, and X is selected from the group consisting of H, N(R.sub.2), SR, OR' or halogen, wherein R is H, lower(C.sub.1 -C.sub.4)alkyl, aryl or mixtures thereof, and the pharmaceutically-acceptable salts thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.