Dihydropyridine depot formulation

US4933186A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Andreas Ohm · Neuss, DE
• Helmut Luchtenberg · Niederkassel, DE
• Manfred Bucheler · Overath, DE
• Josef Schmoll · Wermelskirchen, DE
• Roland Rupp · Bensberg, DE
• Eduard Porges · Cologne, DE
• Takaaki Nishioka · Kobe, JP

Key dates

• Filing date: Aug 4, 1988
• Grant date: Jun 12, 1990
• Expiry date: Aug 4, 2008

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P9/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A pharmaceutical formulation tablet with a long-lasting action for 1 to 2 daily doses having a diameter between about 0.5 and 15 mm and comprising PA0 (a) a rapid-release core of a dihydropyridine, PA0 (b) a coat containing no active compound and formed of a free-flowing powder mixture or of granules, and PA0 (c) optionally, a further coating of a rapid-release dihydropyridine formulation.