Ethanone oximes and pharmaceutical compositions thereof
US4933344A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 31, 1988 |
| Grant date | Jun 12, 1990 |
| Priority date | — |
| Expiry date | Aug 31, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D339/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Ethanone oximes represented by the following general formula: ##STR1## wherein R.sup.1 represents a cycloalkyl group, aryl group, aralkyl group, aryloxy group, aralkyloxy group, arylthio group or aryl sulfonyl group, those groups being optionally substituted with a substituent selected from an alkyl group having 1 to 3 carbon atoms, an alkoxy group having 1 to 3 carbon atoms and a halogen atom, piperidino group, piperazino group, 4-alkyl substituted piparazino group, imidazolyl group, 4-alkyl substituted imidazolyl group or substituted amino group, PA0 R.sup.2 represents a hydrogen atom or an alkoxy group having 1 to 3 carbon atoms, and PA0 R.sup.3 represents a piperidino group, piperazino group or 4-alkyl substituted piperazino group, or PA0 R.sup.1 and R.sup.2 together with a phenyl group to which they are attached may form a phenothiazin-2-yl group, N-acetyl-phenothiazin-2-yl group, thianthren-2-yl group, dibenzothiophen-3-yl group, dibenzofuran-3-yl group or a group of the formula: ##STR2## wherein R.sup.4 represents a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, or a pharmaceutically acceptable acid addition salts thereof are disclosed. They are a potent antiulc…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.