Lipophilically-substituted piperidine oxadiazolyl compounds and their use in stimulating cognitive functions (II)
US4933353A · kind A · utility
22Cited by
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Key dates
| Filing date | Aug 25, 1988 |
| Grant date | Jun 12, 1990 |
| Priority date | — |
| Expiry date | Aug 25, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
New piperidine compounds having the formula ##STR1## wherein at least one of R.sup.3, R.sup.4, and R.sup.5 are ##STR2## and the other independently are H, C.sub.1-6 -alkyl, wherein R' is H, C.sub.1-8 -alkyl, phenyl, thienyl, cyclopropyl, or C.sub.1-3 -alkoxymethyl; and PA1 R.sup.1 and R.sup.6 independently are H or C.sub.1-6 -alkyl, and wherein ##STR3## and salts thereof with pharmaceutically-acceptable acids. The new compounds are useful in improving the cognitive functions of the forebrain and hippocampus of mammals, and are therefore useful in the treatment of Alzheimer's disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.