Method for preparing crystalline hydrate of oral celphalosporin and its composition
US4933443A · kind A · utility
24Cited by
1References
8Claims
0Family size
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Key dates
| Filing date | Nov 21, 1988 |
| Grant date | Jun 12, 1990 |
| Priority date | — |
| Expiry date | Nov 21, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/545
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An antibacterial, 7.beta.-[(Z)-2-(2-aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4 -carboxylic acid is stable in a (di or tri)-hydrate crystal form. A pharmacologically effective amount of this hydrate is filled in a gelatin hard capsule and sealed by a band of gelatin to make a stable composition for clinical use after storage for a long time.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.