Non-passageable viruses

US4935235A · kind A · utility

Assignee

• The Regents of the University of California · US

Inventors

• William J. Rutter · San Francisco, US
• Howard Goodman · Newtown, US

Key dates

• Filing date: Dec 1, 1987
• Grant date: Jun 19, 1990
• Expiry date: Dec 1, 2007

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S930/223
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

What is disclosed is a protein immunoreactive with antibodies raised against HBsAg, which protein has the formula: X-S-Y, S represents a peptide residue of the hepatitis B virus S-protein, Y is OH or NH.sub.2 and X is selected from the pre-S1/pre-S2 peptide residue, the pre S2 peptide residue and a fragment of the pre-S1/pre-S2 peptide residue containing at least a 9 amino acid portion of the C-terminal sequence of pre-S2.