3-[.omega.-(3,5-Di-t-butyl-4-hydroxyphenyl)alkyl]pyrroles, and anti-inflammatory uses thereof
US4935440A · kind A · utility
2Cited by
13References
21Claims
0Family size
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Key dates
| Filing date | Feb 21, 1989 |
| Grant date | Jun 19, 1990 |
| Priority date | — |
| Expiry date | Feb 21, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D207/36
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
3-[.omega.-(3,5-Di-t-butyl-4-hydroxyphenyl)alkanoyl]-pyrroles and their de-oxy analogs, for example, 3-(3,5-di-t-butyl-4-hydroxybenzyl)pyrrole, 2-chloro-4-(3,5-di-t-butyl-4-hydroxybenzoyl)pyrrole, 3-(3,5-di-t-butyl-4-hydroxybenzoyl)pyrrole and 3-[2-(3,5-di-t-butyl-4-hydroxyphenyl)-1-oxoethyl]pyrrole, have high pharmacological potency as anti-inflammatory, analgesic and antipyretic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.